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Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary study

The cysteine protease caspase-1 plays a crucial part in the inflammatory process due to its ability to proteolitically activate proinflammatory cytokine precursors, such as interleukin (IL)-1β and IL-18. Multiple sclerosis is a chronic inflammatory demyelinating disease of the CNS in which the patho...

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Detalhes bibliográficos
Main Authors: Furlan, R, Filippi, M, Bergami, A, Rocca, M, Martinelli, V, Poliani, P, Grimaldi, L, Desina, G, Comi, G, Martino, G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736665/
https://ncbi.nlm.nih.gov/pubmed/10567499
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