Reduced virulence of Candida albicans mutants affected in multidrug resistance.

Disruption of a multidrug resistance gene (CaMDR1) in Candida albicans resulted in mutant strains that colonized mouse kidneys to very high levels but were markedly reduced in their virulence. No obvious differences in several properties related to colonization and dissemination were noted among MDR...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Becker, J M, Henry, L K, Jiang, W, Koltin, Y
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.11.4515-4518.1995
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