Reduced virulence of Candida albicans mutants affected in multidrug resistance.

Disruption of a multidrug resistance gene (CaMDR1) in Candida albicans resulted in mutant strains that colonized mouse kidneys to very high levels but were markedly reduced in their virulence. No obvious differences in several properties related to colonization and dissemination were noted among MDR...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Becker, J M, Henry, L K, Jiang, W, Koltin, Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.11.4515-4518.1995
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