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Is the Ala12 variant of the PPARG gene an "unthrifty allele"?
Background: The thrifty genotype hypothesis proposes that genetic susceptibility to type 2 diabetes results from the positive selection of "thrifty" alleles in the past. A corollary of this hypothesis is that genetic variants protecting against the development of diabetes are "unthrif...
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BMJ Group
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1736098/ https://ncbi.nlm.nih.gov/pubmed/15994875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.026765 |
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