Large genomic deletions inactivate the BRCA2 gene in breast cancer families

Background: BRCA1 and BRCA2 are the two major genes responsible for the breast and ovarian cancers that cluster in families with a genetically determined predisposition. However, regardless of the mutation detection method employed, the percentage of families without identifiable alterations of thes...

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Detalhes bibliográficos
Main Authors: Agata, S, Dalla, P, Callegaro, M, Scaini, M, Menin, C, Ghiotto, C, Nicoletto, O, Zavagno, G, Chieco-Bianchi, L, D'Andrea, E, Montagna, M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2005
Assuntos:
Online Mutation Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735936/
https://ncbi.nlm.nih.gov/pubmed/16199546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.032789
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