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Common variants at the PCOL2 and Sp1 binding sites of the COL1A1 gene and their interactive effect influence bone mineral density in Caucasians

Background: Osteoporosis, mainly characterised by low bone mineral density (BMD), is a serious public health problem. The collagen type I alpha 1 (COL1A1) gene is a prominent candidate gene for osteoporosis. Here, we examined whether genetic variants at the COL1A1 gene can influence BMD variation. M...

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Detalhes bibliográficos
Main Authors: Liu, P, Lu, Y, Long, J, Xu, F, Shen, H, Recker, R, Deng, H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735608/
https://ncbi.nlm.nih.gov/pubmed/15466008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.019851
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