Pre-test prediction models of BRCA1 or BRCA2 mutation in breast/ovarian families attending familial cancer clinics

Objective: To test whether statistical models developed to calculate pre-test probability of being a BRCA1/2 carrier can differentiate better between the breast/ovarian families to be referred to the DNA test laboratory. Study design: A retrospective analysis was performed in 109 Spanish breast/ovar...

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Detalhes bibliográficos
Main Authors: de la Hoya, M, Diez, O, Perez-Segura, P, Godino, J, Fernandez, J, Sanz, J, Alonso, C, Baiget, M, Diaz-Rubio, E, Caldes, T
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735524/
https://ncbi.nlm.nih.gov/pubmed/12843322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.40.7.503
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