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The effect of a single BRCA2 mutation on cancer in Iceland

Objective: To estimate the risk of malignant diseases in families of probands with the same mutation in the BRCA2 gene. Design: A cohort study using record linkage of a breast cancer family resource and the Icelandic Cancer Registry. Setting: Iceland. Subjects: Families of 995 breast cancer patients...

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Bibliographic Details
Main Authors: Tulinius, H, Olafsdottir, G, Sigvaldason, H, Arason, A, Barkardottir, R, Egilsson, V, Ogmundsdottir, H, Tryggvadottir, L, Gudlaugsdottir, S, Eyfjord, J
Format: Artigo
Language:Inglês
Published: BMJ Group 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735175/
https://ncbi.nlm.nih.gov/pubmed/12114473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.39.7.457
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