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Screening for microsatellite instability target genes in colorectal cancers
Background: Defects in the DNA repair system lead to genetic instability because replication errors are not corrected. This type of genetic instability is a key event in the malignant progression of HNPCC and a subset of sporadic colon cancers and mutation rates are particularly high at short repeti...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Group
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1735006/ https://ncbi.nlm.nih.gov/pubmed/12414815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.39.11.785 |
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