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Heterogeneous tissue distribution of a mitochondrial DNA polymorphism in heteroplasmic subjects without mitochondrial disorders

CONTEXT—Several maternally inherited point mutations of the mitochondrial genome cause mitochondrial disorders, but the correlation between genotype and phenotype remains obscure in many cases. The same mutation may cause various diseases, probably because of a different tissue distribution.
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Detalhes bibliográficos
Main Authors: Kirches, E., Michael, M., Warich-Kirches, M., Schneider, T., Weis, S., Krause, G., Mawrin, C., Dietzmann, K.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734867/
https://ncbi.nlm.nih.gov/pubmed/11333867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.38.5.312
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