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Heterogeneous tissue distribution of a mitochondrial DNA polymorphism in heteroplasmic subjects without mitochondrial disorders

CONTEXT—Several maternally inherited point mutations of the mitochondrial genome cause mitochondrial disorders, but the correlation between genotype and phenotype remains obscure in many cases. The same mutation may cause various diseases, probably because of a different tissue distribution.
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Hlavní autoři: Kirches, E., Michael, M., Warich-Kirches, M., Schneider, T., Weis, S., Krause, G., Mawrin, C., Dietzmann, K.
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734867/
https://ncbi.nlm.nih.gov/pubmed/11333867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.38.5.312
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