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Contribution of the MHC region to the familial risk of coeliac disease

Susceptibility to coeliac disease is genetically determined by possession of specific HLA-DQ alleles, acting in concert with one or more non-HLA linked genes. The pattern of risk seen in sibs and twins in coeliac disease is most parsimonious with a multiplicative model for the interaction between th...

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Detalhes bibliográficos
Main Authors: Bevan, S, Popat, S, Braegger, C, Busch, A, O'Donoghue, D, Falth-Magnusson, K, Ferguson, A, Godkin, A, Hogberg, L, Holmes, G, Hosie, K, Howdle, P, Jenkins, H, Jewell, D, Johnston, S, Kennedy, N, Kerr, G, Kumar, P, Logan, R, Love, A, Marsh, M, Mulder, C, Sjoberg, K, Stenhammer, L, Walker-Smith, J, Marossy, A, Houlston, R
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734425/
https://ncbi.nlm.nih.gov/pubmed/10507725
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