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Relative power of linkage and transmission disequilibrium test strategies to detect non-HLA linked coeliac disease susceptibility genes

BACKGROUND—Susceptibility to coeliac disease is genetically determined by possession of specific HLA DQ alleles, acting in concert with one or more non-HLA linked genes. The pattern of familial risk is most parsimonious with a multiplicative model for the interaction between these two classes of gen...

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Detalhes bibliográficos
Main Authors: Bevan, S, Popat, S, Houlston, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727705/
https://ncbi.nlm.nih.gov/pubmed/10517901
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