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Microdeletions in FMR2 may be a significant cause of premature ovarian failure

Genetic causes of premature ovarian failure (POF) include X chromosome deletions and fragile X (FRAXA) premutations. While screening a cohort of women with POF for FRAXA premutations, a more distal trinucleotide repeat, FRAXE, was also tested. We found an unexpected excess of FRAXE alleles with appa...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Murray, A., Webb, J., Dennis, N., Conway, G., Morton, N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Group 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734234/
https://ncbi.nlm.nih.gov/pubmed/10528856
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