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Level of receptor-associated protein moderates cellular susceptibility to pseudomonas exotoxin A.

Pseudomonas exotoxin A (PE) enters mammalian cells via a receptor-mediated endocytic pathway. The initial step in this pathway is binding to the multiligand receptor termed the alpha 2-macroglobulin receptor/low-density lipoprotein receptor-related protein (LRP). Binding of toxin, and of the many ot...

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Detalhes bibliográficos
Main Authors: Mucci, D, Forristal, J, Strickland, D, Morris, R, Fitzgerald, D, Saelinger, C B
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC173396/
https://ncbi.nlm.nih.gov/pubmed/7622212
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