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Level of receptor-associated protein moderates cellular susceptibility to pseudomonas exotoxin A.

Pseudomonas exotoxin A (PE) enters mammalian cells via a receptor-mediated endocytic pathway. The initial step in this pathway is binding to the multiligand receptor termed the alpha 2-macroglobulin receptor/low-density lipoprotein receptor-related protein (LRP). Binding of toxin, and of the many ot...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Mucci, D, Forristal, J, Strickland, D, Morris, R, Fitzgerald, D, Saelinger, C B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173396/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7622212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.8.2912-2918.1995
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