The Ebola virus VP35 protein functions as a type I IFN antagonist

An assay has been developed that allows the identification of molecules that function as type I IFN antagonists. Using this assay, we have identified an Ebola virus-encoded inhibitor of the type I IFN response, the Ebola virus VP35 protein. The assay relies on the properties of an influenza virus mu...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Basler, Christopher F., Wang, Xiuyan, Mühlberger, Elke, Volchkov, Victor, Paragas, Jason, Klenk, Hans-Dieter, García-Sastre, Adolfo, Palese, Peter
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17334/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220398297
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