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The Ebola virus VP35 protein functions as a type I IFN antagonist

An assay has been developed that allows the identification of molecules that function as type I IFN antagonists. Using this assay, we have identified an Ebola virus-encoded inhibitor of the type I IFN response, the Ebola virus VP35 protein. The assay relies on the properties of an influenza virus mu...

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Detalhes bibliográficos
Main Authors: Basler, Christopher F., Wang, Xiuyan, Mühlberger, Elke, Volchkov, Victor, Paragas, Jason, Klenk, Hans-Dieter, García-Sastre, Adolfo, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17334/
https://ncbi.nlm.nih.gov/pubmed/11027311
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