Human lung cancer and p53: The interplay between mutagenesis and selection
It is an almost consensus opinion that the major carcinogenic risk of tobacco smoke is in its direct mutagenic action on DNA of cancer-related genes. The key data supposedly linking smoke-induced mutations to lung cancer were obtained from the adduct spectrum of the p53 tumor suppressor gene. Result...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035769/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.180320897 |
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