Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers

Cancer–testis antigen NY-ESO-1 is one of the most immunogenic tumor antigens defined to date. Spontaneous humoral and CD8+ T-cell responses to NY-ESO-1 are detected in 40–50% of patients with advanced NY-ESO-1-expressing tumors. A clinical trial was initiated to study the immunological effects of in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Jäger, Elke, Gnjatic, Sacha, Nagata, Yasuhiro, Stockert, Elisabeth, Jäger, Dirk, Karbach, Julia, Neumann, Antje, Rieckenberg, Julia, Chen, Yao-Tseng, Ritter, Gerd, Hoffman, Eric, Arand, Michael, Old, Lloyd J., Knuth, Alexander
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220413497
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