Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers

Cancer–testis antigen NY-ESO-1 is one of the most immunogenic tumor antigens defined to date. Spontaneous humoral and CD8+ T-cell responses to NY-ESO-1 are detected in 40–50% of patients with advanced NY-ESO-1-expressing tumors. A clinical trial was initiated to study the immunological effects of in...

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Hlavní autoři: Jäger, Elke, Gnjatic, Sacha, Nagata, Yasuhiro, Stockert, Elisabeth, Jäger, Dirk, Karbach, Julia, Neumann, Antje, Rieckenberg, Julia, Chen, Yao-Tseng, Ritter, Gerd, Hoffman, Eric, Arand, Michael, Old, Lloyd J., Knuth, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC17318/
https://ncbi.nlm.nih.gov/pubmed/11027314
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