Growth of Francisella tularensis LVS in macrophages: the acidic intracellular compartment provides essential iron required for growth.

Murine macrophages supported exponential intracellular growth of Francisella tularensis LVS in vitro with a doubling time of 4 to 6 h. LVS was internalized and remained in a vacuolar compartment throughout its growth cycle. The importance of endosome acidification to intracellular growth of this bac...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Fortier, A H, Leiby, D A, Narayanan, R B, Asafoadjei, E, Crawford, R M, Nacy, C A, Meltzer, M S
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7890413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.4.1478-1483.1995
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