Growth of Francisella tularensis LVS in macrophages: the acidic intracellular compartment provides essential iron required for growth.

Murine macrophages supported exponential intracellular growth of Francisella tularensis LVS in vitro with a doubling time of 4 to 6 h. LVS was internalized and remained in a vacuolar compartment throughout its growth cycle. The importance of endosome acidification to intracellular growth of this bac...

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Autores principales: Fortier, A H, Leiby, D A, Narayanan, R B, Asafoadjei, E, Crawford, R M, Nacy, C A, Meltzer, M S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC173178/
https://ncbi.nlm.nih.gov/pubmed/7890413
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