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Immunohistochemistry for MSH2 and MHL1: a method for identifying mismatch repair deficient colorectal cancer

Colorectal cancers with DNA mismatch repair (MMR) gene mutations characteristically display a high rate of replication errors in simple repetitive sequences detectable as microsatellite instability (MSI). Most are the result of somatic MMR dysfunction; however, a subset are caused by germline mutati...

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Detalhes bibliográficos
Main Authors: Stone, J, Robertson, D, Houlston, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1731447/
https://ncbi.nlm.nih.gov/pubmed/11376026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.54.6.484
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