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Immunohistochemistry for MSH2 and MHL1: a method for identifying mismatch repair deficient colorectal cancer
Colorectal cancers with DNA mismatch repair (MMR) gene mutations characteristically display a high rate of replication errors in simple repetitive sequences detectable as microsatellite instability (MSI). Most are the result of somatic MMR dysfunction; however, a subset are caused by germline mutati...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1731447/ https://ncbi.nlm.nih.gov/pubmed/11376026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.54.6.484 |
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