In vivo growth characteristics of leucine and methionine auxotrophic mutants of Mycobacterium bovis BCG generated by transposon mutagenesis.

Insertional mutagenesis in Mycobacterium bovis BCG, a member of the slow-growing M. tuberculosis complex, was accomplished with transposons engineered from the Mycobacterium smegmatis insertion element IS1096. Transposons were created by placing a kanamycin resistance gene in several different posit...

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Publié dans:	Infect Immun
Auteurs principaux:	McAdam, R A, Weisbrod, T R, Martin, J, Scuderi, J D, Brown, A M, Cirillo, J D, Bloom, B R, Jacobs, W R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7868221/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.3.1004-1012.1995
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