In vivo growth characteristics of leucine and methionine auxotrophic mutants of Mycobacterium bovis BCG generated by transposon mutagenesis.

Insertional mutagenesis in Mycobacterium bovis BCG, a member of the slow-growing M. tuberculosis complex, was accomplished with transposons engineered from the Mycobacterium smegmatis insertion element IS1096. Transposons were created by placing a kanamycin resistance gene in several different posit...

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Main Authors: McAdam, R A, Weisbrod, T R, Martin, J, Scuderi, J D, Brown, A M, Cirillo, J D, Bloom, B R, Jacobs, W R
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC173102/
https://ncbi.nlm.nih.gov/pubmed/7868221
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