Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.

We have recently demonstrated that the macrophage L-arginine-dependent cytotoxic pathway effectively kills the virulent Erdman strain of Mycobacterium tuberculosis in vitro via the generation of toxic reactive nitrogen intermediates by the enzyme nitric oxide synthase. This report demonstrates that...

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Detalles Bibliográficos
Autores principales: Chan, J, Tanaka, K, Carroll, D, Flynn, J, Bloom, B R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC173063/
https://ncbi.nlm.nih.gov/pubmed/7529749
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