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Localizing proteins in the cell from their phylogenetic profiles

We introduce a computational method for identifying subcellular locations of proteins from the phylogenetic distribution of the homologs of organellar proteins. This method is based on the observation that proteins localized to a given organelle by experiments tend to share a characteristic phylogen...

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Autors principals: Marcotte, Edward M., Xenarios, Ioannis, van der Bliek, Alexander M., Eisenberg, David
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17303/
https://ncbi.nlm.nih.gov/pubmed/11035803
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