A mutation at histidine residue 135 of toxic shock syndrome toxin yields an immunogenic protein with minimal toxicity.

Ítems similars

• Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome.
  per: Bonventre, P F, et al.
  Publicat: (1993)
• Effect of chemical modification of histidine and tyrosine residues in toxic shock syndrome toxin 1 on the serologic and mitogenic activities of the toxin.
  per: Kokan-Moore, N P, et al.
  Publicat: (1989)
• A toxic shock syndrome toxin 1 mutant that defines a functional site critical for T-cell activation.
  per: Cullen, C M, et al.
  Publicat: (1995)
• Biological activity of toxic shock syndrome toxin 1 and a site-directed mutant, H135A, in a lipopolysaccharide-potentiated mouse lethality model.
  per: Stiles, B G, et al.
  Publicat: (1995)
• Site-directed mutagenesis of histidine residues in Clostridium perfringens alpha-toxin.
  per: Nagahama, M, et al.
  Publicat: (1995)