Avirulence of rough mutants of Shigella flexneri: requirement of O antigen for correct unipolar localization of IcsA in the bacterial outer membrane.

Mutations in the lipopolysaccharide (LPS) of Shigella spp. result in attenuation of the bacteria in both in vitro and in vivo models of virulence, although the precise block in pathogenesis is not known. We isolated defined mutations in two genes, galU and rfe, which directly affect synthesis of the...

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Библиографические подробности
Главные авторы: Sandlin, R C, Lampel, K A, Keasler, S P, Goldberg, M B, Stolzer, A L, Maurelli, A T
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC172982/
https://ncbi.nlm.nih.gov/pubmed/7528731
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