Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin.

Colonization of the mucosa of the stomach and the duodenum by Helicobacter pylori is the major cause of acute and chronic gastroduodenal pathologies in humans. Duodenal ulcer formation strongly correlates with the expression of an antigen (CagA) that is usually coeexpressed with the vacuolating cyto...

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izdano v:	Infect Immun
Principais autores:	Xiang, Z, Censini, S, Bayeli, P F, Telford, J L, Figura, N, Rappuoli, R, Covacci, A
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1995
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7806390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.1.94-98.1995
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