Knockout mutants of Actinobacillus pleuropneumoniae serotype 1 that are devoid of RTX toxins do not activate or kill porcine neutrophils.

The Actinobacillus pleuropneumoniae RTX-toxins ApxI, ApxII, and ApxIII are important virulence factors of this swine pathogen. It is hypothesized that the Apx toxins are deleterious to defense cells of the host, enabling the bacterium to infect the host. To confirm this, we studied the effect on por...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Autores principales:	Jansen, R, Briaire, J, Smith, H E, Dom, P, Haesebrouck, F, Kamp, E M, Gielkens, A L, Smits, M A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7806365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.1.27-37.1995
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