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Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma.

The reverse transcriptase from human immunodeficiency virus type 1 was purified from the virus to near homogeneity. The enzyme was shown to possess both RNA-dependent and DNA-dependent DNA-synthesizing activity. Activated DNA as a heteropolymeric substrate was used as efficiently as was the homopoly...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: König, H, Behr, E, Löwer, J, Kurth, R
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2482702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.12.2109
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