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Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors

BACKGROUND—Activated hepatic stellate cells (HSC) are central to the pathogenesis of liver fibrosis, both as a source of fibrillar collagens that characterise fibrosis and matrix degrading metalloproteinases and their tissue inhibitors, the TIMPs.
AIMS—To test the hypothesis that HSC apoptosis is cr...

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Autores principales: Issa, R, Williams, E, Trim, N, Kendall, T, Arthur, M, Reichen, J, Benyon, R, Iredale, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728234/
https://ncbi.nlm.nih.gov/pubmed/11247901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.4.548
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