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Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethane

BACKGROUND—Non-steroidal anti-inflammatory drugs (NSAIDs) have been reported to protect against the development of colon cancer. However, the mechanism(s) by which NSAIDs exert their effects is not clear.
AIMS—The aim of this study was to examine the effects of NSAIDs on mRNA expression of tumour su...

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Detalhes bibliográficos
Main Authors: Kishimoto, Y, Takata, N, Jinnai, T, Morisawa, T, Shiota, G, Kawasaki, H, Hasegawa, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728141/
https://ncbi.nlm.nih.gov/pubmed/11076880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.6.812
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