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Sulindac increases the expression of APC mRNA in malignant colonic epithelial cells: an in vitro study.

BACKGROUND--Sulindac is a non-steroidal anti-inflammatory drug which induces regression of colonic polyps in patients with familial adenomatous polyposis. Animal and in vitro studies have shown that both the sulphide metabolite of sulindac, which is able to inhibit cyclo-oxygenase, and the sulphone...

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Detalhes bibliográficos
Main Authors: Schnitzler, M, Dwight, T, Robinson, B G
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383152/
https://ncbi.nlm.nih.gov/pubmed/8707116
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