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Effect of age on the intracortical accumulation kinetics of gentamicin in rats.

We have evaluated the influence of age on the intracortical accumulation kinetics of gentamicin in conscious male rats by using a short-term infusion model. Animals were infused with gentamicin over a 6-h period and achieved individual steady-state levels in serum ranging from 0.5 to 12 micrograms/m...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Beauchamp, D, Gourde, P, Bergeron, M G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2610510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.11.2006
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