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Effect of age on the intracortical accumulation kinetics of gentamicin in rats.

We have evaluated the influence of age on the intracortical accumulation kinetics of gentamicin in conscious male rats by using a short-term infusion model. Animals were infused with gentamicin over a 6-h period and achieved individual steady-state levels in serum ranging from 0.5 to 12 micrograms/m...

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Main Authors: Beauchamp, D, Gourde, P, Bergeron, M G
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC172804/
https://ncbi.nlm.nih.gov/pubmed/2610510
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