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Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis

BACKGROUND AND AIM—The treatment of ulcerative colitis (UC) with 5-aminosalicylic acid (5-ASA) does not have the same therapeutic effect in all patients. We tested the hypothesis that the effectiveness of the drug is related to its mucosal concentration.
PATIENTS—Twenty one UC patients receiving ora...

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Autores principales: Frieri, G, Giacomelli, R, Pimpo, M, Palumbo, G, Passacantando, A, Pantaleoni, G, Caprilli, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728031/
https://ncbi.nlm.nih.gov/pubmed/10940280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.3.410
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