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Surface hydrophobicity of the rat colonic mucosa is a defensive barrier against macromolecules and toxins

BACKGROUND—Mucosal surface hydrophobicity is a key factor of the gastric acid defence barrier. In the colon, surface hydrophobicity is high but its biological function remains unexplored.
AIMS—To investigate the functional changes of the barrier due to removal of the surface active phospholipid laye...

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Bibliographic Details
Main Authors: Lugea, A, Salas, A, Casalot, J, Guarner, F, Malagelada, J
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727902/
https://ncbi.nlm.nih.gov/pubmed/10716681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.46.4.515
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