Pharmacokinetics and tissue penetration of Sch 39304 in granulocytopenic and nongranulocytopenic rabbits.

We studied the plasma pharmacokinetics and tissue penetration of Sch 39304 (SCH), a new antifungal triazole, in granulocytopenic [G(+)] and nongranulocytopenic [G(-)] rabbits. Five female New Zealand White G(-) rabbits were given a single oral dose of 2 mg of SCH per kg of body weight. Levels in pla...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Lee, J W, Lin, C, Loebenberg, D, Rubin, M, Pizzo, P A, Walsh, T J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2610504/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.11.1932
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