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Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease

BACKGROUND—The factors determining why less than 10% of heavy drinkers develop advanced alcoholic liver disease (ALD) remain elusive, although genetic factors may be important. Interleukin 10 (IL-10) is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. Several po...

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Hlavní autoři: Grove, J, Daly, A, Bassendine, M, Gilvarry, E, Day, C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727883/
https://ncbi.nlm.nih.gov/pubmed/10716685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.46.4.540
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