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Heterozygotes for HFE mutations have no increased risk of advanced alcoholic liver disease

Background—Iron overload is common in the livers of alcoholics and may play a role in disease pathogenesis. An MHC like gene, HFE, has recently been identified that is mutated in most patients with hereditary haemochromatosis (C282Y in 90% and H63D in 45% of the remainder). 
Aim—To examine the hypot...

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Detalhes bibliográficos
Main Authors: Grove, J, Daly, A, Burt, A, Guzail, M, James, O, Bassendine, M, Day, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727223/
https://ncbi.nlm.nih.gov/pubmed/10189855
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