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Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis

BACKGROUND—The pathogenesis of pancreatic fibrosis is unknown. In the liver, stellate cells play a major role in fibrogenesis by synthesising increased amounts of collagen and other extracellular matrix (ECM) proteins when activated by profibrogenic mediators such as cytokines and oxidant stress. 
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Main Authors: Apte, M, Haber, P, Darby, S, Rodgers, S, McCaughan, G, Korsten, M, Pirola, R, Wilson, J
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727467/
https://ncbi.nlm.nih.gov/pubmed/10075961
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