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Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphate.

3'-Azido-2',3'-dideoxyuridine-5'-triphosphate was found to be a potent and highly selective inhibitor of human immunodeficiency virus type 1 and simian immunodeficiency virus reverse transcriptases. The affinity of 3'-azido-2',3'-dideoxyuridine-5'-triphosphate for the reverse transcriptases was simi...

Повний опис

Збережено в:
Бібліографічні деталі
Опубліковано в::Antimicrob Agents Chemother
Автори: Eriksson, B F, Chu, C K, Schinazi, R F
Формат: Artigo
Мова:Inglês
Опубліковано: American Society for Microbiology (ASM) 1989
Предмети:
Онлайн доступ:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1729
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