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Structure-epileptogenicity relationship of quinolones with special reference to their interaction with gamma-aminobutyric acid receptor sites.

The relationship between the chemical structure and epileptogenic activity of quinolones was investigated. When the quinolones were administered intravenously to mice concomitantly with oral biphenylacetic acid, a major metabolite of the nonsteroidal antiinflammatory drug fenbufen, enoxacin, norflox...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Akahane, K, Sekiguchi, M, Une, T, Osada, Y
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556076/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1704
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