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Phosphorylation of murine p53 at Ser-18 regulates the p53 responses to DNA damage

Ser-15 of human p53 (corresponding to Ser-18 of mouse p53) is phosphorylated by ataxia-telangiectasia mutated (ATM) family kinases in response to ionizing radiation (IR) and UV light. To determine the effects of phosphorylation of endogenous murine p53 at Ser-18 on biological responses to DNA damage...

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Autors principals: Chao, Connie, Saito, Shin'ichi, Anderson, Carl W., Appella, Ettore, Xu, Yang
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17273/
https://ncbi.nlm.nih.gov/pubmed/11035798
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