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A rapid method of haplotyping HFE mutations and linkage disequilibrium in a Caucasoid population

Background—HFE mutations are associated with hereditary haemochromatosis. However, a simple method capable of demonstrating the cis/trans arrangement of alleles is lacking, and linkage disequilibrium between HFE alleles and classic HLA loci is unknown. These are important issues as the pathogenic ro...

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Détails bibliographiques
Auteurs principaux: Mullighan, C, Bunce, M, Fanning, G, Marshall, S, Welsh, K
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727064/
https://ncbi.nlm.nih.gov/pubmed/9616322
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