Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors

Demonstrating in vivo interaction of two important biomolecules and the relevance of the interaction to a biological process have been difficult issues in biomedical research. Here, we report the use of a homology modeling approach to establish the significance of protein interactions in governing t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Parrish, Jay, Metters, Helen, Chen, Lin, Xue, Ding
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.210391597
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