Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors
Demonstrating in vivo interaction of two important biomolecules and the relevance of the interaction to a biological process have been difficult issues in biomedical research. Here, we report the use of a homology modeling approach to establish the significance of protein interactions in governing t...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.210391597 |
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